Cladribine to Treat Relapsing Forms of Multiple Sclerosis
نویسندگان
چکیده
منابع مشابه
Cladribine in aggressive forms of multiple sclerosis.
Cladribine (2-chlorodeoxyadenosine) is an immunosuppressant drug previously evaluated in multiple sclerosis (MS) with variable results. We report six patients with aggressive relapsing MS who despite a poor response to other therapies had a favourable clinical evolution after cladribine. Four women and two men with a rapid increase in the number and severity of relapses leading to increasing di...
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INTRODUCTION Multiple sclerosis (MS) is a chronic immune-mediated disorder of the central nervous system leading to progressive neurodegeneration and disability. Until 2010, all approved disease-modifying drugs for MS required parenteral administration, which is associated with suboptimal adherence. It was anticipated that new approaches to treatment, including oral agents such as cladribine ta...
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ژورنال
عنوان ژورنال: Neurotherapeutics
سال: 2017
ISSN: 1933-7213,1878-7479
DOI: 10.1007/s13311-017-0573-4